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ylbI [2019-08-01 09:50:39]

pantetheine-phosphate adenylyltransferase

locus

BSU_15020

5.65

18.04 kDa

protein length

161 aa Sequence Blast

gene length

486 bp Sequence Blast

function

lipopolysaccharide biosynthesis

product

pantetheine-phosphate adenylyltransferase

essential

yes

2.7.7.3

synonyms

coaD

Outlinks

KEGG BsubCyc SubtiList UniProt Expression Browser

Genomic Context

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categories

[category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.6|Cell wall/ other/ based on similarity]

[category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

Gene

Coordinates

1,570,078 1,570,563

Phenotypes of a mutant

essential [Pubmed|28189581]

The protein

Catalyzed reaction/ biological activity

ATP + pantetheine 4'-phosphate = diphosphate + 3'-dephospho-CoA (according to Swiss-Prot)

Protein family

bacterial coaD family (single member, according to UniProt)

Structure

[PDB|1O6B] (complex with ADP)

[SW|Localization]

cytoplasm (according to Swiss-Prot)

Expression and Regulation

Operons

genes

description

[Pubmed|22383849]

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genes

[gene|65FA4B3738C2A5995F019099743C782ADD15C338|ylbH]-[gene|6DAAEF20B68139A732FDCDABD0C420A0C928D373|ylbI]

description

[Pubmed|22383849]

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Biological materials

Mutant

MGNA-B360 (ylbI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1359 NBRP B. subtilis, Japan]

References

28189581